期刊文献+

畜禽Nramp1基因抗病作用的研究进展 被引量:2

Advances on the Disease Resistance of Nramp1 Gene in Livestock and Poultry
下载PDF
导出
摘要 Nramp1基因作为影响畜禽抗病育种中抗病力的主要候选基因之一,其蛋白可抵抗多种胞内菌的侵染,从而提高畜禽抗病力。主要叙述Nramp1基因的结构特点和作用机理,综述了Nramp1基因与抗病性状的关系,并对其应用前景进行了展望。 Nramp 1 gene is one of candidate genes on disease resistance in breeding of livestock and poultry. Nramp 1 protein can resist a variety of intracellular bacteria, so the disease resistance of animal could be improved. The main characters and mechanism of Nramp 1 gene and the relationship between Nramp 1 gene and disease resistance characters were briefly reviewed, furthermore the application prospect of Nramp 1 gene was put forward.
出处 《畜牧与饲料科学》 2012年第7期79-81,共3页 Animal Husbandry and Feed Science
基金 国家现代农业(兔)产业技术体系(CARS-44E-11) 福建省公益类科研院所专项(2011R1025-1) 福建省农业科学院青年基金项目(2011QC-13) 福建省农业科学院畜牧兽医研究所所长基金(2011S01)
关键词 Nramp1基因 抗病作用 畜禽 Nramp 1 gene disease resistance livestock and poultry
  • 相关文献

参考文献21

  • 1BLACKWELL J M.Structure and function of the natural- resistance -associated macrophage protein (Nrampl),a candidate protein for infectious and autoimmune disease susceptibility [ J ].Mol Med Today, 1996,2 (5) : 205-211.
  • 2GOVONI G,GROS P.Macrophage NRAMP1 and its role in resistance to microbial infections [J].Inflamm Res, 1998,47 (7) :277-284.
  • 3BELOUCHI A, CELLIER M, KWAN T, et al.The macrophage- specific membrane protein Nramp controlling natural resistance to infections in mice has homologues expressed in the root system of plants [J].Plant Mol Biol, 1995,29 (6): 1181-1196.
  • 4吴宏梅,王立贤.NRAMP1基因研究进展及其在抗病育种中的应用[J].中国畜牧兽医,2005,32(4):26-28. 被引量:17
  • 5McDERMID J M,PRENTICE A M.Iron and infection:effects of host iron status and the iron-regulatory genes haptoglobin and NRAMP1 (SLCllA1)on host-pathogen interactions in tuberculosis and HIV [ J ].Clin Sci, 2006,110 ( 5 ) : 503-524.
  • 6薛尚军,贾静敏,刘宏,石建中,曹果清.NRAMP1基因的研究进展[J].畜牧与饲料科学,2011,32(1):28-30. 被引量:2
  • 7GOVONI G,VIDAL S,CELLIER M,et al.Genomic structure, promoter sequence, and induction of expression of the mouse Nramp 1 gene in macrophages [ J ].Genomics, 1995,27 ( 1 ) : 9- 19.
  • 8LAM-YUK-TSEUNG S, PICARD V, GROS P.Identification of a tyrosine-based motif (YGSI) in the amino terminus of Nrampl (Slcllal) that is important for lysosomal targeting [J].J Biol Chem,2006,281 (42) :31677-31688.
  • 9CANONNE-HERGAUX F,CALAFAT J,RICHER E,et al. Expression and subcellular localization of NRAMPI in human neutrophil granules [J ] .Blood, 2002,100 ( 1 ) : 268-275.
  • 10ZHANG G L,WU H,ROSS C R,et al.Cloning of porcine NRAMP1 and its induction by lipopolysaceharide,tumor necrosis factor alpha, and intedeukin- 1 beta: role of CD 14 and mitogen-aetivated protein kinases [ J ].Infect Immun, 2000,68 (3) : 1086-1093.

二级参考文献79

共引文献44

同被引文献15

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部