Rho/Rho激酶在肺癌中的作用及其潜在治疗靶点
被引量：2
Function and possible therapeutic target of the Rho/Rho-kinase in lung cancer
摘要
Rho蛋白在细胞内起到分子开关的作用，Rho／ROCK信号通路在细胞的粘附、变形、迁移、增殖、凋亡等多种行为方面起到重要调控作用。Rho蛋白的异常表达或激活被发现与肺癌细胞生物学特征和患者预后等有显著相关性，并可能成为潜在治疗靶点。现就Rho／ROCK信号通路在肺癌中的作用及其潜在治疗作用做一综述。
出处
《中华肺部疾病杂志（电子版）》
CAS
2012年第4期51-54,共4页
Chinese Journal of Lung Diseases(Electronic Edition)
基金
江苏省自然科学基金资助项目(BK2011658)
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