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晚期非小细胞肺癌患者体液标本表皮生长因子受体突变基因检测的进展 被引量：4

Progress of the detection of epidermal growth factor receptor in body fluids for advanced non-small cell lung cancer
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摘要 尽管肺癌的诊断、分期、治疗日趋规范化，但由于缺乏有效的早期筛查制度和方法，加之传统化疗的疗效出现平台期，导致肺癌患者总体预后依然很差，5年生存率仅为16％。随着分子肿瘤学的发展，发现表皮生长因子受体（epidermalgrowthfactorreceptor，EGFR）是原癌基因c—erbBl的表达产物，其突变参与了肿瘤的生长、侵袭等过程。
作者 王沣 操乐杰
机构地区 安徽医科大学附属省立医院呼吸内科
出处 《中华肺部疾病杂志（电子版）》 CAS 2012年第4期69-72,共4页 Chinese Journal of Lung Diseases(Electronic Edition)
关键词 非小细胞肺癌 表皮生长因子受体 突变基因
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献22

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二级参考文献35

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共引文献9

同被引文献29

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引证文献4

二级引证文献12

中华肺部疾病杂志（电子版）
2012年 第4期

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