经尿道前列腺切除术与开放手术治疗良性前列腺增生症的远期疗效

Evaluationof the long-term effect of transurethral resection of the prostate and open prostatectomy for benign prostatic hyperplasia

目的评价开放手术(OP)、经尿道前列腺切除术(TURP)不同手术方式的远期疗效,为临床治疗方案的选择提供依据。方法采用前瞻性队列研究,将入组的良性前列腺增生症(BPH)患者随机采用不同手术方式进行治疗,并分别在手术前、手术后3个月、6个月、12个月进行随访观察。采用国际前列腺症状评分(IPSS)、良性前列腺增生症患者的生活质量专用量表(BPHQLS)评价不同时间各组患者的IPSS、生活质量状况。结果两组IPSS得分呈现曲线下降趋势、生活质量得分呈现曲线上升趋势。OP、TURP组在手术后3、6、12个月时下尿路症状无差别(P>0.05);术后3个月、12个月时生活质量OP组(278.95±19.68,291.91±59.14)高于TURP组(252.59±18.85,253.49±29.52)(P<0.05)。结论 OP在提高患者的远期生活质量方面优于TURP。

Objective To evaluate the long-term effect of open prostatectomy（OP） and transurethral resection of the prostate（TURP） in the treatment of benign prostatic hyperplasia（BPH）.Methods A prospective cohort study was conducted.Patients with BPH were treated with OP or TURP.In the 3rd,6th and 12th month during follow-up,IPSS and BPHQLS were adopted to evaluate IPSS and quality of life of patients.Results The score of IPSS of both groups reduced,while the score of quality of life rose.The lower urinary tract symptoms of both groups had no difference in the 3rd,6th and 12th month.The quality of life of the OP group（278.95±19.68,291.91±59.14） was higher than that of TURP group（252.59±18.85,253.49±29.52） in the 3rd and 12th month.Conclusions Both OP and TURP can improve the lower urinary tract symptoms,but OP has more strength in improving the long-term quality of life than TURP.