不同方法干预子宫肌瘤临床疗效比较

目的探讨在子宫肌瘤中运用不同方法的效果。方法将收治的47例患者均为我院门诊及住院患者,按照临床研究的随机、对照原则,并结合患者自身情况,分别给予米非司酮药物、子宫动脉栓塞术组和腹腔镜子宫肌瘤剔除术,观察疗效及随访生活质量。结果与药物组比较,手术1、2组有效率均较高,差异具有统计学意义(P<0.05,P<0.01);手术2组优于手术1组,差异具有统计学意义(P<0.05)。随访6个月发现,药物组在躯体功能、整体健康状况得分上低于手术1、2组,但在情感功能得分则优于手术1、2组,差异均具统计学意义(P<0.05)。结论腹腔镜子宫肌瘤剔除术、子宫动脉栓塞术成功率好,但米非司酮对于患者预后情感功能上改善明显,这可能与手术对于患者心理造成的影响有关。

Objective To explore the Clinical comparison of different methods for the treatment of uterine fibroids. Methods The 47 patients admitted to our hospital patients according to clinical studies,randomized,control principle,and with the patient＇s own condition, were given mifepristone treatnient group,operation treatment of uterine artery embolization group and laparoscopic myomectomy observe the curative effect and the follow--up of quality of life. Results Operation operation was successful in all 2 groups,and the drug group,2 groups of l,operation efficiency is high,the difference was statistically significant（P〈0.05,P〈0. 01）; operation 2 group was better than the operation of 1 groups,the difference was statistically significant（P〈0.05）.Follow up of 6 months found,drug group in somatic function,overall health status score lower than 1, 2 sets of operation,but in emotional function score better than the operation 1,2 groups,differences were statistically significant（P〈0.05）.Conclusion Laparoscopic myomectomy for uterine artery embolization, success rate, but the prognosis of the patients with mifepristone for emotional function improved significantly,which may be related to operation for patients with psychological impact on.