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咪达唑仑、芬太尼复合丙泊酚与右美托咪定复合丙泊酚用于老年人无痛胃肠镜可行性的比较 被引量:16

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摘要 目的:观察小剂量咪达唑仑、芬太尼复合丙泊酚与小剂量右美托咪定复合丙泊酚用于老年人无痛胃肠镜的安全性和可行性。方法:50例行无痛胃肠镜的老年患者,随机分为咪达唑仑、芬太尼复合丙泊酚麻醉组(D组)和右美托咪定复合丙泊酚麻醉组(P组)。每组25例,D组检查前5min,先缓慢静脉注射咪达唑仑0.2~0.25 mg,芬太尼20~25 mg,检查开始前缓慢静注丙泊酚1 mg/kg;P组10 min内缓慢静注右美托咪定0.5μg/kg后,缓慢静脉注射丙泊酚1 mg/kg,待睫毛反射消失后即可置入纤维镜,两组术中若出现体动必要时追加丙泊酚0.2~0.5 mg/kg。记录患者检查前(T0),检查中(T1),检查后(T2),苏醒时间,HR、SBP、SpO2的变化,不良反应发生情况及患者舒适度。结果:T1时两组HR慢于(T0),SBP明显低于T0时(P>0.05),T2时D组HR、SBP高于P组(P>0.05),两组的SpO2,不良反应,舒适度差异无统计学意义。结论:小剂量咪达唑仑、芬太尼复合丙泊酚与小剂量右美托咪定复合丙泊酚用于老年人无痛胃肠镜均具有良好安全性,且小剂量咪达唑仑、芬太尼复合丙泊酚经济适用,适合在基层医院推广。
出处 《黔南民族医专学报》 2012年第2期97-100,共4页 Journal of Qiannan Medical College for Nationalities
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