唾液SIgA、溶菌酶含量与牙周病关系的探讨

Study on the Relationship Between Salivary Contents of SIgA, Lysosome and Periodontitis

目的:探讨了牙周病患者唾液SIgA和溶菌酶含量的变化及临床意义。方法:应用放射免疫分析检测32例牙周病患者唾液SIgA含量、免疫扩散法检测溶菌酶含量,并与35名正常健康人作比较。结果:牙周病患者唾液SIgA和溶菌酶含量均非常显著地高于正常人组(P<0.01),经治疗1个月后与正常人组比较仍有显著性差异(P<0.05)。结论:检测牙周病患者唾液SIgA和溶菌酶含量的变化对临床观察预后有重要的临床价值。

Objective To study the relationship between sailic levels of SIgA,Lys and periodontitis.Method Sailic SIgA（with RIA）and Lys（with immunodiffusion-assay） levels were measured in 32 patients with periodontitis both before and after treatment as well as in 35 normal controls.Results Before treatment,the saliac SIgA and Lys levels in the patients were significantly higher than those in controls（P〈0.01）.After treatment for 1 month.The sailic SIgA and Lys levels,though dropped markedly,but remained significantly higher than the controls（P〈0.05）.Condusion Changes of Sailic SIgA and Lys levels contents after treatment might be of prognostic and observing importance in patients with periodontitis.