支气管肺炎患儿血清IGF-Ⅱ、hs-CRP和LT检测的临床应用

Clinical Application of Determination the Changes on Serum IGF-Ⅱ,hs-CRP and LT Levels in Pediatric Patients with Bronchopneumonia

目的:探讨了支气管肺炎患儿治疗前后血清IGF-Ⅱ、hs-CRP和LT水平的变化及临床意义。方法:应用放免法、免疫比浊法和酶联法对33例支气管肺炎患儿进行了治疗前后血清IGF-Ⅱ、hs-CRP和白三烯(leukotriene,LT)测定,并与35名正常健康儿做比较。结果:支气管肺炎患儿在治疗前血清IGF-Ⅱ、hs-CRP和LT水平非常显著地高于正常儿组(P<0.01),经治疗2周后则与正常儿组比较无显著性差异(P>0.05)。结论:检测支气管肺炎患儿治疗前后血清IGF-Ⅱ、hs-CRP和LT水平的变化对疾病的诊断、治疗和预后判断均具有一定临床价值。

Objective To explore the clinical application of changes on serum IGF-Ⅱ,hs-CRP and LT levels after treatment in pediatric patients with bronchopneumonia.Methods Serum IGF-Ⅱ（with RIA）,serum hs-CRP（with immunoturbidimetry）,serum LT（with ELISA） levels were determined in 33 pediatric patients with bronchopneumonia both before and after treatment as well as in 35 normal healthy controls.Results Before treatment,serum IGF-Ⅱ,hs-CRP and LT levels in the patients were significantly higher than the controls（P〈0.01）.After treatment for two weeks,the serum IGF-Ⅱ,hs-CRP and LT levels were no significant difference from those in controls（P〉0.05）.Conclusion Detection of serum IGF-Ⅱ,hs-CRP and LT levels in pediatric patients with branch-opneumnia possess definite value for diagnosis,treatment and prediction.