3Marchesini G,Brizi M,Bianchi G. Metformin in non-alcoholic steatohepatitis[J].The Lancet,2001,(9285):893-894.doi:10.1016/S0140-6736(01)06042-1.
4Nair S,Diehl AM,Wiseman M. Metformin in the treatment of non-alcoholic steatohepatitis:a pilot open label trial[J].Alimentary Pharmacology and Therapeutics,2004.23-28.doi:10.1111/j.1365-2036.2004.02025.x.
5Lavine JE,Schwimmer JB,Van Natta ML. Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents:the TONIC randomized controlled trial[J].Journal of the American Medical Association,2011.1659-1668.
6Uygun A,Kadayifci A,Isik AT. Metformin in the treatment of patients with non-alcoholic steatohepatitis[J].Alimentary Pharmacology and Therapeutics,2004.537-544.doi:10.1111/j.1365-2036.2004.01888.x.
7Neuschwander-Tetri BA,Brunt EM,Wehmeier KR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone[J].Hepatology,2003.1008-1017.
8Ratziu V,Giral P,Jacqueminet S. Rosiglitazone for nonalcoholic steatohepatitis:one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial[J].Gastroenterology,2008.100-110.
9Ratziu V,Charlotte F,Bernhardt C. Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis:results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial[J].Hepatology,2010.445-453.
10Torres DM,Jones FJ,Shaw JC. Rosiglitazone versus rosiglitazone and metformin versus rosiglitazone and losartan in the treatment of nonalcoholic steatohepatitis in humans:A 12-month randomized,prospective,open-label trial[J].Hepatology,2011.1631-1639.
8Alberti KG, Zimmet PZ. Definition, diagnosis, and classification of diabetes mellitus and its complications. Part l: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation[J]. Diabet Med, 1998,15:539-553.3167.
9The expert committee on the diagnosis and classification of diabetes mellitus. Follow-up report on the diagnosis of diabetes mellitus[J]. Diabetes Care,2003,26:3160-3167.
10Anand SS, Yusuf S. Stemming the global tsunami of cardiovascular disease[J]. Lancet,2011,12:529-532.