血液滤过治疗重症糖尿病非酮症性高渗综合症

Hemofiltration for severe diabetic nonketotic hyperosmolar syndrome

目的分析血液滤过治疗重症糖尿病非酮症性高渗综合症的效果。方法对我院21例使用血液滤过治疗的重症糖尿病非酮症性高渗综合症患者（实验组）与28例使用常规治疗的重症糖尿病非酮症性高渗综合症患者（对照组）进行比较。比较两组间血糖下降至8mmol／L的时间、渗透压恢复至320mOsm／L的时间，抢救成功率、病死率。结果实验组患者血糖及渗透压能够更快地恢复正常，其抢救成功率更高，病死率更低，与对照组患者比较差异有显著性，P〈0．05。结论使用血液滤过治疗重症糖尿病非酮症性高渗综合症的效果更好，值得在临床应用。

Objective To analyze the efficacy of hemofiltration in the treatment of severe diabetic nonketotic hyperosmolar syndrome （ NKHS ）. Methods The clinical data on 21 patients undergoing hemofiltration for NKHS （ study group ） were compared with those on 28 patients receiving conventional treatment for NKHS （ control group ）. Time to a decline in blood glucose to a level of 8 mmoL/l_, time to restoration of osmotic pressure to a level of 320 mOsm/L, survival rate, and mortality rate were compared between the two groups. Results In the study group, levels of blood glucose and osmotic pressure returned to normal more rapidly. It, as compared with the control group, had a higher success rate and a lower mortality rate, with a significant difference （ P〈 0.05 ）. Conclusions Hemofiltration is more effective in the treatment of severe diabetic nonketotic hyperosmolar syndrome and is worth popularizing clinically.