甲氨蝶呤肌注和超声定位孕囊注药治疗子宫瘢痕部位妊娠的比较

Comparitive study on the effects of intramuscular and ultrasound Iocatization sac injection of methotrexat on the patients with cesarean scar pregnancy

目的探讨甲氨蝶呤肌注和超声定位孕囊注药对治疗子宫瘢痕部位妊娠的比较。方法选取40例子宫瘢痕部位妊娠患者，随机分为注药组和对照组各20例，两组患者分别采用经阴道超声引导定位孕囊注入甲氨蝶呤50mq和单次肌注甲氨蝶呤50mg进行治疗，观察两组患者的临床疗效、不良反应、治疗1周后超声显示妊娠包块大小、血β-HCG下降至正常所需时间和治疗后住院时间。结果注药组的治疗效果明显优于对照组，不良反应少，差异有显著性（P〈0．05）。结论甲氨蝶呤肌注和经阴道超声引导定位孕囊注入均是治疗子宫瘢痕部位妊娠的有效方法，但后者的疗效更好，值得推广。

Objective To observe the comparison of the effect of intramuscular and ultrasound Iocatization sac injection of methotrexat on the patients with cesarean scar pregnancy. Methods 40 case of cesarean scar pregnancy were randomly divided into the control group and the test group, the control group received intramuscular methotrexat, and the test group received ultrasound Iocatization sac injection methotrexat, the following indexes of the two groups were compared： the clinical curative effects,adverse effect,the size of gravidity mass after treat one week,the resolution time for reduction of 13 - HCG and length of stay. Results The therapeutic efficacy of test group was better than that of the control group, and with less adverse effect, there was significant difference between the two groups （P〈0.05）. Conclusion Intramuscular and ultrasound Iocatization sac injection of methotrexat is an effective method for the patients with cesarean scar pregnancy, but the latter is more effective and has less adverse reactions ,which is worth of promotion.