黑色丘疹性皮病一例

Dermatosis papulosa nigra： a case report

患者女，36岁，胸腹部多发黑褐色丘疹10余年，逐渐增多。体检：前胸、腹部皮肤可见散在数十个黑褐色扁平丘疹，直径1-3mm，表面光滑，部分呈乳头瘤样，无融合。腹部皮损组织病理检查：表皮轻度角化过度，棘层增厚，皮突延长，互相连接成网状，棘层内可见假性角囊肿形成，基底层色素增加，真皮浅层血管周围稀疏淋巴组织细胞浸润。诊断：黑色丘疹性皮病。

A 36-year-old female presented with muhiple dark brown papules on the chest and abdomen for more than 10 years, which had gradually increased in number. Physical examination revealed dozens of dark brown, flat papules measuring 1-3 mm in diameter in the chest and abdomen. Most of the lesions had a smooth surface, and some lesions gave a papilloma-like appearance, with no confluent trend. Biopsy of abdominal lesions showed mild hyperkeratosis of epidermis, acanthosis, extension of epidermal protrusions forming a reticulated appearance, horn pseudocysts in prickle cell layer, enhanced pigmentation of basal layer, and a sparse lymphocytic perivascular infiltrate in superficial dermis. A diagnosis of dermatosis papulosa nigra （DPN） was made.