我院2009～2011年二类精神药品的应用情况分析

Application Analysis on the Second Class Psychotropic Drugs in Our Hospital from 2009 to 2011

目的评价我院二类精神药品的应用情况与发展趋势,为药品管理及合理用药提供参考。方法采用世界卫生组织推荐的限定日剂量为指标的分析方法,对我院2009～2011年二类精神药品的应用进行回顾性分析。结果我院苯二氮类及巴比妥类二类精神药品的年销售金额和用药频度逐年上升,氯硝西泮、阿普唑仑和艾司唑仑的用药频度较高,以扎来普隆为代表的新一代非苯二氮类药物用量有下降趋势。结论二类精神药品应用结构稳定,临床用药基本合理。苯二氮类药物占临床用药的主导地位。

Objective To evaluate the application situation and development tendency of the second class psychotropic drugs in our hospital and provide references for the drug management and rational drug use. Methods Using the daily dose limit recommended by the World Health Organization（WHO） as the indicator, to retrospectively analyze the application of the second class psychotropic drugs. Results The annual sales and drug use frequency of benzodiazepine and barbiturate psychotropic drugs are rising year by year, with higher use frequency of Clonazepam, Alprazolam and Estazolam. As a representative of the new generation non-benzodiazepine drugs, Zaleplon has been used in a decreased tendency. Conclusion The application structure of the second class psychotropic drugs is stable, and the clinical use of them is basically reasonable. Benzodiazepine drugs have the dominant position in the clinical use.