从“郁”论治——应用自拟方解郁清毒散治疗带状疱疹146例临床分析

Study on clinical efficacy of resolving depression and detoxification powder(Chinese herbal medicine powder) in treatment of 146 cases of herpes zoster

目的探讨从"郁"论治带状疱疹及应用自拟方解郁清毒散治疗带状疱疹的疗效。方法通过对带状疱疹多年来的诊治经验,结合目前带状疱疹的发病特点,应用Hamilton汉密尔顿抑郁量表(HAMD)(24项)为评定工具对带状疱疹患者进行心理调查与分析。并根据病因病机采用行气补虚、泻火解毒、通络止痛的方法,并结合现代医学药理研究成果组成的自拟方解郁清毒散治疗该病146例。结果带状疱疹患者存在不同程度的抑郁,应用自拟方解郁清毒散治疗该病总有效率达95.89%。结论解郁清毒散是治疗带状疱疹的有效药物,且临床应用简单、方便、价廉,能显著减少后遗神经痛的发生,亦无不良反应,值得临床推广使用。

Objective To explore the clinical effect of self - made prescription resolving depression and detoxification powder （Jieyu Qingdu San） originated from the theoretical concept of traditional Chinese medicine in treatment of patients with herpes zoster. Methods Accord- ing to experience in treatment of herpes zoster, authors adopted the Hamilton Rating Scale for Depression （HAMD） （24 items） as rating system to study and analyze the psychological status of patients with herpes zoster. According to the pathogenesis, therapeutic method for moving qi （gas） and to nourish xu （weakness）, purging fire to detoxify and freeing the collateral vessels to relieve pain were combined with modern pharmacological knowledge to formulate the self - made prescription for resolving depression and detoxifying powder in treatment of 146 patients with herpes zoster. Satisfactory effectiveness had been obtained. Results Most of patients with herpes zoster suffered from depression in varying degree. The clinical effect of self - made prescription resolving depression and detoxifying powder in treatment of patients with herpes zoster, is satisfactory, and its ef- fective rate reached 95.89%. Conclusiott The application of resolving depression and detoxification powder shows satisfactory efficacy in treat- ment of patients with herpes zoster and it can dramatically reduce the incidence of post - therapeutic neuralgia without any adverse reactions. Along with its reasonable price and convenience in clinical application, it is recommended for widely clinical application.