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结肠透析配合尿毒清颗粒保留灌肠治疗慢性肾功能衰竭的疗效 被引量:13

Effects of colonic dialysis combined with uremic clearance granule retention-enema on patients with chronic renal failure
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摘要 目的:观察结肠透析配合尿毒清颗粒保留灌肠治疗慢性肾功能衰竭(CRF)的临床疗效。方法:将80例CRF患者随机分为观察组与对照组各40例。两组常规治疗相同,对照组采用尿毒清颗粒直接保留灌肠;观察组先行结肠透析,之后以尿毒清颗粒保留灌肠。观察两组治疗前后临床症状和血肌酐(Scr)、血尿素氮(BUN)及血清β2-微球蛋白(β2-MG)指标的变化。结果:两组治疗后临床症状体征、Scr、BUN、β2-MG较治疗前均有不同程度的改善(P<0.01或P<0.05),观察组改善优于对照组(P<0.01),两组总有效率比较差异有显著性(P<0.01)。结论:尿毒清灌肠治疗CRF有一定疗效,而结肠透析配合尿毒清颗粒保留灌肠治疗CRF疗效更为显著。 Objective To observe the effects of colonic dialysis combined with uremic clearance granule retention-enema on patients with chronie renal failure (CRF). Methods Eighty patients with CRF were randomly divided into control group (n = 40) and treatment group (n = 40). Patients in control group received routine western medications and uremic clearance granule retention-enema, and those in treatment group were treated with colonic dialysis combined with uremic clearance granule retention-enema besides the same routine treatment. The changes of clinical symptoms and the levels of serum creatinine (Scr), blood urea nitrogen (BUN), and β2 micro- globulin (β2-MG) before and after the treatments were observed. Results After the treatments, the clinical symptoms and the levels of Ser, BUN, and β2-MG were ameliorated (P 〈 0.01 or P 〈 0.05), and those in treatment group were better than those in control group (P 〈 0.01 ). There was a significant difference of the effective rate between the two groups (P 〈 0.01 ). Conclusion Uremic clearance granule retention-enema is effective in treating CRF, when combined with colonic dialysis, a better therapeutic effect can be observed.
机构地区 解放军
出处 《实用医学杂志》 CAS 北大核心 2012年第15期2528-2530,共3页 The Journal of Practical Medicine
关键词 肾功能衰竭 慢性 结肠透析 中药疗法 灌肠 尿毒清颗粒 Renal failure, chronic Colonic dialysis Chinese traditional therapy Clysma Uremic clearance granule
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