摘要
本文采用二甲苯致小鼠耳廓肿胀法、棉球致小鼠肉芽肿法观察藏药西藏棱子芹的抗炎作用,采用热板法、醋酸扭体法观察藏药西藏棱子芹的镇痛作用。结果表明藏药西藏棱子芹能明显抑制二甲苯所致小鼠耳廓肿胀和棉球所致小鼠肉芽肿;能提高小鼠对热板疼痛的阈值,减少小鼠扭体反应的次数,延长醋酸所致小鼠扭体反应的潜伏时间。藏药西藏棱子芹具有显著的抗炎镇痛作用,值得开发研究。
The anti-inflammatory effects of Tibetan Medicine Pleurospermum hookeri var.thomsonii in mice was observed in test of ear swelling caused by xylene and cotton pellet-induced granuloma mouse method.The analgesic effect of P.hookeri var.thomsonii in mice was observed in hot-plate test and acetic acid-induced writhing.The experiments showed that P.hookeri var.thomsonii could apparently inhibit auricle swelling induced by xylene and cotton pellet-induced granuloma,obviously prolong the pain threshold of temperature stimuli,decrease the number of writhe induced by acetic acid,and reduce the latent twisted body reaction times in mice.Tibetan Medicine P.hookeri var.thomsonii has both anti-inflammatory and analgesic effects obviously,and is worthy of research and development.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2012年第7期972-975,共4页
Natural Product Research and Development
基金
青海大学国家大学生创新性实验计划项目(091074305)
关键词
西藏棱子芹
抗炎
镇痛
药效学
Pleurospermum hookeri var.thomsonii； anti-inflammatory； analgesic； pharmacodynamics；
