皖南地区74例嗜麦芽窄食单胞菌的分布及耐药分析

Analysis of 74 Strains of Stenotrophomonas Maltophilia in Southern Regiongs of Anhui

目的了解皖南地区嗜麦芽窄食单胞菌的分布情况及耐药性,为临床治疗提供参考。方法对皖南地区2007～2009年检测出的嗜麦芽窄食单胞菌进行回顾性分析。结果患者年龄分布以60岁以上为主,感染部位以肺部为主,感染科室以干部内科为主;74例标本药敏结果耐药率从高到低依次为头孢噻肟87.83%、头孢吡肟64.87%、头孢他啶52.70%、替卡西林/克拉维酸41.89%、氯霉素24.32%、头孢哌酮/舒巴坦21.62%、复方新诺明21.62%、左旋氧氟沙星14.86%、米诺环素13.51%。结论作为条件致病菌,嗜麦芽窄食单胞菌的感染已呈增加趋势,应引起临床足够重视,药物治疗应首选四环素类、喹诺酮类和磺胺类。

Objective To investigate the distribution and antibiotic resistance of Stenotrophomonas maltophilia （SMA） in southern regions of Anhui so as to provide reference for clinical medication. Method To review the SMA, which had been isolated from 2007 to 2009 in southern regions. Results The predominant susceptible ages was more than 60, the main infected part was pulmonary and the main distribution was cadre medicine ;the resistant rates of 74 specimens to cefotaxime, cefepime, ceftazidime, ticarcillin/clavulanic, chloramphenicol, cefoperazone/sulbactam, sulfamethoxazole, lev- ofloxacin and minocycline were 87.83%,64.87%,52.70%,41.89%,24.32%,21.62%,21.62%,14.86% and 13.51% re- spectively. Conclusion We should take great importance to the increasing infected rate of Stenortophomonas maltophilia as one of the most important opportunity bacteria of hospital. Tetracycline quinolones and sulfa were the optimal choice for antibiotic therapy.