期刊文献+

甲状腺抗体检测在甲状腺功能诊断中的价值 被引量:9

下载PDF
导出
摘要 目的探讨抗甲状腺球蛋白抗体(TGAb)、抗甲状腺过氧化物酶抗体(TPO-Ab)检测在甲状腺功能诊断中的价值。方法用全自动微粒子发光法分析206例甲状腺疾病患者血清中的TGAb、TPO-Ab水平。结果甲状腺功能亢进组、甲状腺功能减退组及桥本甲状腺炎组与单纯性甲状腺肿组及健康对照组比较,TGAb和TPO-Ab定量检测值及阳性率差异均有统计学意义(P值均小于0.01),单纯性甲状腺肿组与健康对照组的TGAb和TPO-Ab定量检测值及阳性率差异无统计学意义。结论联合定量检测TGAb和TPO-Ab有助于甲状腺疾病的诊断。
出处 《检验医学与临床》 CAS 2012年第14期1770-1771,共2页 Laboratory Medicine and Clinic
  • 相关文献

二级参考文献30

共引文献60

同被引文献56

  • 1雷燕芬.生化检验中化学发光免疫测定技术的应用分析[J].世界临床医学,2017,11(12):226-226. 被引量:9
  • 2中华医学会内分泌学分会.中国甲状腺疾病诊治指南[M].//中国内科年鉴.上海:上海第二军医大学出版社,2008:576-594.
  • 3Okosieme OE, Parkes AB, Premawardhana LD, et al. Thyroglobulin : current aspects of its role in autoimmune thyroid disease and thyroid cancer[J]. Minerva Med, 2003,94(5) :319 -330.
  • 4Prummel MF, Wiersinga WM. Thyroid peroxidase autoantibodies in eu- thyroid subjects[ J]. Best Pratt Res Clin Endocrinol Metab, 2005,19 (1):1 -15.
  • 5Kim WG, Yoon JH, Kim WB, et al. Change of serum antithyro- globulin antibody levels is useful for protection of clinical recur- rence in thyroglobulin-negative patients with differentiated thyroid carcinoma[ J]. J Clin Endoerinol Metab, 2008, 93 : 4683 - 4689. '.
  • 6Feldt Rasmussen U. Analytical and clinical performa- nce goals for testing autoantibodies to thyroperoxi- dase, thyroglobulin, and thyrotropin receptor[J]. Clin- ical Chemistry, 1996,42 ( 1 ) : 160-163.
  • 7Belyavin G, Trotter WR. Investigations of thyroid antigens reacting with Hashimoto sera: Evidence for an antigen other than thyroglobulin[J]. The Lancet, 1959,1(774) 648-652.
  • 8Zophel K, Saller B, Wunderlich G, et al. Autoantibod- ies to thyroperoxidase(TPOAb) in a large population of euthyroid subjects:implications for the definition of TPOAb reference intervals[J]. Clinical Laboratory, 2002,49(11/12) :591-600.
  • 9Sundbeck G, Ed+n S, Jagenburg R, et al. Prevalence of serum antithyroid peroxidase antibodies in 85-year-old women and men[J]. Clinical Chemistry, 1995,41 (5) : 707-712.
  • 10Bjero T, Holmen J, Kruger O. Prevalence of thyroid diease, thyroid dysfunction and thyroid peroxidase an- tibodies in a large unselected population. The health study of Nord-Trendelag (HUNT) [ J ]. European Journal of Endocrinology, 2000,143 ( 5 ) : 639-647.

引证文献9

二级引证文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部