前列腺癌患者术前焦虑与术后疼痛的相关性分析

Correlation between Anxiety and Postoprerative Pain in Patients with Prostate Cancer

目的:研究前列腺癌患者术前焦虑与术后疼痛的相关性。方法:选取40例行择期性前列腺癌根治术且美国麻醉医师学会(American Society of Anesthesiologists,ASA)评级为I～II级的前列腺癌患者。在其术前1d,采用焦虑状态-特质评分问卷(the State-Trait Anxiety Inventory,STAI)进行焦虑评估。采用静脉和吸入复合麻醉,术后使用静脉吗啡自控镇痛泵。术后采用视觉模拟评分(visual analogue scale,VAS)对疼痛进行评估,记录术后24h的平均VAS值。将患者术前焦虑评分与术后疼痛评分以及术后疼痛评分与吗啡使用量进行相关性分析。结果:患者术前焦虑状态评分为35.0±8.1,术前焦虑特质评分为35.8±11.5,术后平均VAS值为38.2±9.5。术前焦虑状态与术后疼痛呈线性正相关(r=0.747,P<0.01),患者术前焦虑特质与术后疼痛无显著相关性(P>0.05)。患者术后吗啡使用量为(7.6±3.36)mg,术后疼痛与术后吗啡使用量无显著相关性(P>0.05)。结论:前列腺癌患者的术前焦虑状态程度与术后疼痛强度呈正相关,它可以作为术后疼痛强度的预测因素。

Objective：To evaluate the correlation between preoperative anxiety and postoperative pain in patients with prostate cancer. Methods：A total of 40 patients scheduled for elective radical prostatectomy with American Society of Anesthesiology （ASA） grades I- II were enrolled. The questionnaires of the State-Trait Anxiety Inventory （STAI） were completed a day be- fore the surgery. All patients underwent conventional intravenous-inhalation combined anesthesia. Intravenous patient-con- trolled analgesia （PCA） with morphine was used to manage the postoperative pain. The postoperative pain was estimated by visual analogue scale （VAS） during the 24 hours after surgery. The relationships among STAI scores, VAS scores and mor- phine consumptions have been analyzed. Results： The state of anxiety inventory score was 35 ± 8. 1, which was significantly correlated （P〈0.05） with the postoperative pain score of 38.2 ± 9.5. A linear regression analysis showed that the state of anxiety could predict the intensity of postoperative pain, but the trait anxiety was not a significant predictor. The average con- sumption of morphine was （7.6 ± 3.36 ）mg which had no significant correlation with postoperative pain （P〉0.05）. Conclu- sions： Patients with higher anxiety state levels felt more postoperative pain. The state of anxiety was a predictor of postopera- tive pain in patients with prostate cancer.