围术期清洁切口预防性应用抗菌药物调查分析

Investigation and analysis of prophylactic use of antimicrobial drugs in the clean incision operation during perioperative period

目的调查分析围术期清洁切口(Ⅰ类切口)预防性应用抗菌药物的情况,为临床合理用药提供参考。方法根据卫生部门发布的相关规定回顾性调查分析患者性别、年龄、科室、诊断、手术日期、手术名称及手术持续时间、选用抗菌药物品种、首次给药时机、用法用量和抗菌药物疗程及其费用等资料。结果清洁切口(Ⅰ类切口)围术期预防性使用抗菌药物比例占68.00%;使用青霉素或第1代头孢菌素占46.47%,药物选择不符合规定者占34.70%,用药疗程不符合规定者占52.35%,用法用量不符合规定者占35.88%,首次给药时机不符合规定者占11.18%。结论清洁切口(Ⅰ类切口)预防性应用抗菌药物比例不符合相关规定,药物品种选择、抗菌药物疗程、用法用量及首次给药时机均存在不符合相关规定的现象。

Objective To investigate and analyze the prophylactic use situation of antimicrobial drugs n the clean incisions（type I incision） during perioperative period to provide reference for clinical rational drug use. Methods According to the relevant provisions issued by the Ministry of Health, the retrospective analysis was performed on the patients＇ gender, age, depart- ment, diagnosis, surgery date, surgical name and duration, use of antimicrobial drugs varieties, first administration timing, dosage, etc. Results The proportion of prophylactic antibiotics use in the clean incisions（type I incision） during the perioperative peri- od accounted for 68.00%. The use of penicillin or the first generation cephalosporins accounted for 46.47%. Irregularly selecting drug accounted for 34.70%. Irregular treatment course accounted for 52.35%. The usage and dosage in inconfarmity to stipula- tion accounted for 35.88%. The first dose timing in inconformity to stipulation accounted for 11.18%. Conclusion The proportion of prophylactic use of antimicrobial drugs in the clean incisions （type I incision） is in inconformity to the relewmt provisions. In the aspects of the first timing of administration, usage and dosage of drugs selections of antimicrobial drugs and treatment course the phenomena in inconformity to relevant provisions exist.