期刊文献+

网膜素研究进展 被引量:7

下载PDF
导出
摘要 中心性(内脏)肥胖与胰岛素抵抗、2型糖尿病(T2DM)、心血管病和代谢综合征的关系程度高于外周(皮下)肥胖,而皮下脂肪(SAT)的沉积与减少心血管病危险性有关,但二者病理生理机制至今仍不很清楚。2003年美国马里兰大学Yang等由内脏网膜脂肪组织的cDNA文库证实了一个新的脂肪点特异性脂肪因子.网膜素(omentin)。该网膜素基因定位于染色体lq22-q23区,而该区又与不同人群的T2DM基因染色体定位有关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第15期3335-3338,共4页 Chinese Journal of Gerontology
  • 相关文献

参考文献30

  • 1YangR,Xu A,Pray J,et al.Cloning of omentin,a new adipocytokine from omental fat tissue in humans(J).Diabetes,2003;(suppl 1):A1.
  • 2Fu M,Gong DW,Damcott C,et al.Systematic analysis of omentin 1 and omentin 2 on 1q23 as candidate genes for type 2 diabetes in the old order amish(J).Diabetes,2004;53:A59.
  • 3Viomet N,Hani EH,Dupont S,et al.Genomewide search for type 2 dia-betes susceptibility genes in French whites:evidence for a novel suscepti-bility locus on chromosome 1q21-q24(J).Am J Hum Genet,2000;67(6):1470-80.
  • 4Campos DB,Palin M-F,Bordignon V,et al.The'beneficial'adipokines in reproduction and fertility(J).Int J Obes,2008;32(2):223-31.
  • 5Tsuji S,Uehori J,Matsumoto M,et al.Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wal(lJ).J Bio Chem,2001;276:23456-63.
  • 6Schaffler A,Neumeier M,Herfarth H,et al.Genomic structure of human omentin,a new adipocytokine expressed in omentaladipose tissue(J).Biochim Biophys Acta,2005:1732:96-102.
  • 7LeeJK,Schnee J,Pang M,et al.Human homologs of Xenopus oocyte cor-tical granule lectin XL35(J).Glycobiology,2001;11(1):65-73.
  • 8Suzuki Y,Shin K,Lonnerdal B.Molecular cloning and functional expres-sion of a human intestinal lactoferrin receptor(J).Biochemistry,2001;40(51):15771-9.
  • 9YangR,Lee M,Hu H,et al.Identification of omentin as a novel depot-specific adipokine in human adipose tissue:possible role in modulating insulin action(J).Am J Physiol Endocrinol Metab,2006;290(6):E1253-61.
  • 10Xiang K,Wang Y,Zheng T,et al.Genome-wide search for type 2 diabe-tes/impaired glucose homeostasis susceptibility genes in the Chinese sig-nificant linkage to chromosome 6q21-q23 and chromosome 1q21-q24(J).Diabetes,2004;53(1):228-34.

同被引文献68

  • 1潘峰,崔建和,周传文,任建国,李东海.非酒精性脂肪性肝病抵抗素、脂联素与肝纤维化相关性研究[J].陕西医学杂志,2008,37(11):1500-1503. 被引量:6
  • 2周丽斌,陈名道.脂肪因子和代谢综合征[J].中国医学科学院学报,2006,28(6):840-844. 被引量:4
  • 3乐杰.妇产科学[M].7版.北京:人民卫生出版社,2010:366.
  • 4邵肖梅,叶鸿瑁,丘小汕.实用新生儿学[M].第4版.北京:人民卫生出版社,2012:63-64.
  • 5Botero D, Lifshitz F.Intrauterine growth retardation and long-term effects on growth[J].Curr Opin Pediatr, 1999, 11 ( 4 ) : 340-347.
  • 6Schaffler A, Neumeicr M, Herfarth H, et al.Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue[J].Biochim Biophys Acta, 2005-, 1732 ( 23 ) : 96-102.
  • 7Guillod-Maximin E, Roy A F, Vacher C M, et al.Adiponectin receptors are expressed in hypothalamus and colocaiized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons[J].J Endocrinel, 2009, 200 ( 12 ) : 95-105.
  • 8Souza Batista C M, Yang R Z, Lee M J, et al.Omentin plasma levels, and gene espression are decreased in obesity[J].Diabetes, 2007, 56 ( 10 ) : 1655-1661.
  • 9Yamawaki H, Kuramoto J, Kameshima S, et al.Omentin, a novel adipocytokine inhibits TNF-induced vascular inflammation in human endothelial cells[J].Biochem Biophys Res Commun, 2011, 408 ( 2 ): 339-343.
  • 10Yamawaki H, Tsubaki N, Mukohda M, et al.Omentin, a novel adipokine, induces vasodilation in rat isolated blood vessels[J]. Bioehem Biophys Res Commun, 2010, 393 ( 12 ) : 668-672.

引证文献7

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部