应用Westgard方法评价决定图判断Sysmex XE5000全血细胞分析仪性能

Application of Westgard method evaluation decision chart(MEDx) for judging method performance of Sysmex XE5000 hematologic analyzer

目的应用Westgard方法评价决定图判断Sysmex XE5000型全血细胞分析仪系统性能的可接受性。方法以实验室室内质控结果的变异系数(CV%)反应方法的不精密度,以实验室参加卫生部临床检验中心2012年室间质评的偏倚(Bias%)反映方法的不准确度,在Westgard方法评价决定图上绘制操作点,并判断各项目的方法性能的可接受性。结果WBC、RBC、HGB、HCT、MCH、MCV、MCHC和PLT的CV%值分别为:1.89、0.6、0.6、0.79、0.9、0.92、1.3和3.2,偏倚分别为-5.71、-2.55、-1.46、-0.27、2.23、0.46、0.27和-6.97。结论采用Westgard方法评价决定图能方便地评价检测仪器的检测性能,Sysmex XE5000全血细胞分析仪主要检测指标性能优秀。

Objective To evaluate the performance of Sysmex XE5000 hematology analyzer by Westgard method evaluation decision chart （MEDx）. Methods The percentage coefficient of variation （CV%） accquired from laboratory internal quality control and bias% from external quality assurance （EQA） were taken as mea- surement imprecision and inaccuracy respectively for analyzer. Westgard method evaluation decision chart （MEDx） is a graphical tool that provides an easy way to judge a method＇s performance. MEDx chart took CV % and bias% as operating point＇s x and y-coordinate. Operating points of parameters WBC, RBC, HGB, MCV, MCH, MCHC and PLT in MEDx chart were ploted to judge the performance of hetaatology analyzer XE5000. Results The CV% of WBC, RBC, HGB, HCT, MCH, MCV, MCHC and PLT were 1.89, 0.6, 0.6, 0.79, 0.9, 0.92, 1.3 and 3.2 respectively, and the bias% of those parameters were -5.71, -2.55, -1.46, -0.27, 2.23, 0.46, 0.27 and -6.97 respectively. All the operating points droped in excellent performance region in MEDx. Con- clusiotm Objective decisions on the performance of methods can be made quickly and easily with the aid of a MEDx, Sysmex XE5000 hematology analyzer possesses excellent performance on WBC, RBC, HGB, HCT, MCV, MCH, MCHC and PLT.