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沉默信息调节因子2同源蛋白1与软骨细胞 被引量:4

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摘要 沉默信息调节因子2同源蛋白1(SIRT1)具有广泛的生物学功能,主要包括能量代谢,延长寿命,调节细胞分化及细胞凋亡,应对应激状态下细胞存活等。研究证实,SIRT1基因在人类软骨细胞及软骨组织中存在表达,对延缓软骨细胞衰老、凋亡起重要作用。该文就SIRT1结构与生物学功能、对软骨细胞增殖分化的影响及与其他因素之间的相互作用等方面研究作一综述。
出处 《国际骨科学杂志》 2012年第4期237-239,共3页 International Journal of Orthopaedics
基金 国家自然科学基金(30973025) 卫生部公益性行业专项基金(201002018) 安徽省教育厅自然科学研究基金重点项目(KJ2010A320)
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同被引文献100

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