检测外周血C反应蛋白、纤维蛋白原含量对肛周脓肿诊治的临床意义

Clinical Significance of Detecting Blood Levels of C-reactive Protein and Fibrinogen for Diagnosis and Treat- ment of Perianai Abscess

为探讨检测外周血C反应蛋白（CRP）、纤维蛋白原（FIB）含量对肛周脓肿诊治的临床意义，本研究检测175例肛周脓肿患者及150名健康体检者外周血白细胞总数与分类计数、CRP和FIB含量．并进行对比分析。结果显示，肛周脓肿患者外周血白细胞总数、中性粒细胞百分比、CRP和FIB含量均显著高于健康体检者（P〈0．01），淋巴细胞百分比显著低于健康体检者（P〈0．01）。肛周脓肿患者外周血CRP与FIB含量变化呈正相关（P〈0．01）。结果表明，CRP和FIB可作为早期诊断肛周脓肿的指标，治疗肛周脓肿应在控制感染的同时监测患者凝血功能，以便及时给予抗栓治疗，降低体内FIB含量水平，避免引发严重的并发症。

In order to explore the clinical significance of detecting the content of C-reactive protein（CRP） and fibrinogen（FIB） for diagnosis and treatment of perianal abscess,this study detected the leukocyte total count（LTC） and differential count（LDC） of peripheral blood,as well the content of CRP and FIB from 175 patients with perianal abscess and 150 healthy person undergoing physical examination,and compared analysed. As results,in peripheral blood LTC, the ratio of neutrophilic granulocyte, CRP level and FIB level of the patients with perianal abscess was all higher than the healthy person significantly（ P〈0.01） ,while the ratio of lymphocyte significantly was lower（ P〈0.01）;in the patients the level changes of CRP and FIB was of positive correlation（ P〈0.01）. Results show that CRP and FIB could be serviced as the inde- xes for early diagnosing perianal abscess;in the treatment perianal abscess,at same time of controlling in- fection monitoring blood coagulation function should be done, so that giving antithromhotic therapy,reduc-ing FIB level,thus avoiding severe complication.