晚期胃癌姑息性切除联合术中、术后化疗的临床价值

Clinical values of palliative tumor resection combined with intra-and postoperative chemotherapy for late-staged gastric carcinoma

目的:探究晚期胃癌姑息性切除联合术中、术后化疗的临床价值。方法:67例晚期胃癌患者中,肿瘤姑息性切除联合术中、术后化疗46例(A组),姑息性非切除手术21例(B组)。收集两组临床及随访资料,比较两组患者的生存质量及预后。结果:术后半年、1年、2年生存率A组明显优于B组(P<0.01);术后近期A组较B组生存质量提高(P<0.05)。结论:晚期胃癌姑息性切除联合术中、术后化疗,可提高术后生存率及生存质量。

Objective：To investigate the clinical values of palliative tumor resection combined with intra and postoperative chemotherapy for late-staged gastric carcinoma. Methods ：In 67 patients, postoperative survival rates and quality of life between 46 patients with palliative tumor resection （A group） and 21 patients with unre- sectable operation （B group） was compared retrospectively. Results ：The 0.5- , 1-, and 2-year survival in A group were significantly higher than those in B group（P〈0.01）. In addition, the quality of life of the patients in A group was better than that in B group （P〈0.05）. Conclusions： Compared with unresectable operation, palliative tumor resection combined with intra- and post- operative chemotherapy for the patients with late-staged gastric carcinoma can imorove the oostooerative survival rates and the qualitiv of their life.