正常成人胼胝体磁共振轴位及矢状位DTI定量研究

The quantitative study of corpus callosum in mid-sagittal and transverse DTI in normal adults

目的:研究正常成人胼胝体磁共振轴位扩散张量成像(DTI)与矢状位DTI各向异性(FA)可能的差异,探讨2种测量方法的可靠性。方法:对68例健康志愿者分别行轴位和矢状位DTI扫描,年龄18～78岁。分别测量胼胝体膝部及压部的FA值。对相同部位的轴位和矢状位测量结果进行比较,并行相关性分析。结果:矢状位上测量的胼胝体膝部FA值大于轴位,且两者之间差异有统计学意义(t=-5.833,P<0.001)。胼胝体压部FA值在矢状位与轴位上差异无统计学意义(t=0.435,P>0.05)。结论:矢状位与轴位DTI测量的胼胝体膝部及压部FA值不同,矢状位DTI能研究胼胝体各个区域各向异性的变化。

Objective： To study the possible difference of anisotropy of corpus callosum in mid-sagittal and transverse diffusion tensor imaging（DTI） in normal adults. Methods： Sixty-eight health adult volunteers were collected continuously, the male and female were 35 and 33 respectively, with an age-range from 18 to 78 years. All cases were performed mid-sagittal and trans- verse DTI separately. The fractional anisotropy （FA） values of the genu and splenium of the corpus callosum were measured in FA map. The FA values were analyzed. Results： The FA values of genu was higher in mid-sagittal DTI than that in transverse DTI,and had statistically difference（ t = -5. 833, P 〈0. 001）. The FA values of splenium in mid-sagittal DTI and that in transverse DTI was no statistically difference（ t =0. 435, P 〉0.05）. The FA value of genu was higher than that of splenium in mid-sagittal DTI. The FA value of splenium was higher than that of genu in transverse DTI. Conclusion： The FA values of ge-nu and splenium were different in mid-sagittal and in transverse DTI, the anisotropy of different regions of corpus callosum could be measured in mid-sagittal DTI.