负压创面治疗肝源性糖尿病并发糖尿病足的研究

Research of Hepatogenous Diabetic Foot by NPWT

目的:讨论创面负压治疗促进肝硬化合并糖尿病并发糖尿病足的临床疗效。方法:将30例慢性肝硬化合并糖尿病并发糖尿病足患者随机分为创面负压治疗组和敷料包扎组,观察两组创面细菌负荷及创面微循环血流量变化。结果:清创即刻,负压创面治疗组和敷料包扎组细菌负荷与创面微循环血流量无显著差异(P>0.01);创后3天、6天和9天时,负压创面组创面细菌负荷低于敷料包扎组(P<0.01),创面微循环血流量高于敷料包扎组(P<0.01)。负压创面组创面愈合时间少于敷料包扎组(P<0.01)。结论:负压创面治疗有助于慢性肝硬化并发糖尿病合并糖尿病足的创面愈合。

Objective： To observe the efficacy of local treatment on hepatogenous diabetic ulcer by using Negative pressure wound therapy （NPWT） way. Methods： 30 patients with Hepatogenous diabetic foot were randomized into experimental and control group, using Negative pressure wound therapy and common gauze dressing therapy. Results： After treatment, the bacteria cells of NPWT group was lower than that in common gauze dressing group （P〈0.01）. The blood flow of NPWT group was higher than that in common gauze dress- ing group （P〈0.01）. Conclusion： Negative pressure wound therapy is a good treatment to promote hepatogenous diabetic ulcer healing.