摘要
目的:比较剖宫产术后切口瘢痕妊娠不同治疗方法的有效性。方法:将241例切口瘢痕妊娠患者分为孕囊穿刺组(120例)和动脉栓塞组(121例),比较各组治疗后疗效、血清β-人绒毛膜促性腺激素(β-hCG)恢复至正常时间、出血量、住院时间、转经时间、住院费用以及激素水平。结果:孕囊穿刺组和动脉栓塞组治愈率分别为95.0%和94.2%。动脉栓塞组血β-HCG水平下降快于孕囊穿刺组。孕囊穿刺组和动脉栓塞组血β-HCG恢复至正常时间分别为(49.3±5.4)天和(23.0±3.4)天,两组比较差异有统计学意义(P<0.01)。孕囊穿刺组和动脉栓塞组出血量分别为(71.27±178.81)ml和(30±40)ml,两组比较差异有统计学意义(P<0.01)。孕囊穿刺组和动脉栓塞组住院时间分别为(31.7±5.1)天和(18.3±5.9)天,两组比较差异有统计学意义(P<0.01)。孕囊穿刺组和动脉栓塞组转经时间分别为(49.8±7.3)天和(33.7±12.7)天,两组比较差异有统计学意义(P<0.05)。孕囊穿刺组和动脉栓塞组治疗费用分别为(3 657.12±29.36)元和(10173.47±34.91)元,两组比较差异有统计学意义(P<0.01)。两组治疗前后激素水平比较差异无统计学意义(P>0.05)。结论:子宫动脉栓塞术的疗效明显优于孕囊穿刺术,血β-HCG水平恢复快、出血量少、住院时间短、月经恢复快,是目前值得推广应用的技术。
Objective: To compare the efficacies of different therapies for cesarean scar pregnancy (CSP) . Methods: A total of 241 CSP patients were divided into gestational sac puncture group (120 patients) and artery embolization group (120 patients), then the curative effects, the times for serum 13 - human chorionic gonadotropin ( 13 - hCG) return to normal, the amounts of blood loss during opera- tion, the hospitalization times, the times for menstrual recovery, the hospitalization expenses, and the levels of hormones in the two groups were compared. Results: The cure rates in gestational sac puncture group and artery embolization group were 95.0% and 94. 2%, respec- tively. The descent speed of serum 13 -HCG level in artery embolization group was quicker than that in gestational sac puncture group. The times for serum J3 - hCG return to normal in gestational sac puncture group and artery embolization group were ( 49. 3 ± 5.4 ) days and (23.0 ±3.4) days, respectively, there was statistically significant difference between the two groups (P 〈0. 01 ) . The amounts of blood loss during operation in gestational sac puncture group and artery embolization group were (71.27 ±178. 81 ) ml and (30±40) ml, respec- tively, there was statistically significant difference between the two groups (P 〈 0. 01 ) . The hospitalization times in gestational sac puncture group and artery embolization group were (31.7 ±5.1 ) days and (18.3 ±5.9) days, respectively, there was statistically significant differ- ence between the two groups ( P 〈 0.01 ) . The times for menstrual recovery in gestational sac puncture group and artery embolization group were (49. 8 ±7.3) days and (33.7 -+ 12.7) days, respectively, there was statistically significant difference between the two groups (P 〈 0. 05 ) . The hospitalization expenses in gestational sac puncture group and artery embolization group were ( 3 657. 12 ~ 29. 36 ) Yuan and ( 10 173.47 ~ 34.91 ) Yuan, respectively, there was statistically significant difference between the two groups ( P 〈 0. 01 ) . There was no statistically significant difference in the levels of hormones between before and after treatment in the two groups ( P 〉 0. 05 ) . Conclusion: The curative effect of uterine artery embolization was better than that of gestational sac puncture, the recovery of serum 13 - hCG was faster, the blood loss during operation was fewer, the hospitalization time was shorter, the menstrual recovery was quicker, so uterine artery emboli- zation is a technique worthy to be popularized and applied at present.
出处
《中国妇幼保健》
CAS
北大核心
2012年第22期3448-3451,共4页
Maternal and Child Health Care of China
基金
河南省商丘市科技局科研项目〔20103020〕
关键词
剖宫产
瘢痕妊娠
孕囊穿刺
动脉栓塞
Cesarean section
Scar pregnancy
Gestational sac puncture
Artery embolization