高龄老年院内获得性肺炎60例临床分析

Clinical analysis of 60 senile patients with hospital-acquired pneumonia

目的观察通过选择敏感抗生素联合痰热清治疗高龄老年院内获得性肺炎(HAP)的临床疗效。方法将本院干部病房收治的高龄老年HAP患者60例,随机分成治疗组30例与对照组30例。结果病原学分布依次为:金黄色葡萄球菌、肺炎克雷伯菌、铜绿假单胞菌、鲍氏不动杆菌、大肠埃希菌,尤其以金黄色葡萄球菌检出率最高,感染革兰氏阴性杆菌居多,泛耐药菌的感染和混合感染是治疗困难的根本原因。根据药敏结果选择合适抗生素尤为重要,而敏感抗生素联合痰热清治疗HAP明显优于对照组。结论高龄老年HAP死亡率高,病情凶险,痰热清联合相关抗生素治疗可及时控制感染,对疾病的转归有非常大的帮助。

Objective To observe the clinical efficacy of Tanreqing otics in senile patients with hospital- acquired pneumonia （HAP）. Methods combined with antibi- A total of 60 senile pa- tients with HAP in the Cadres Ward of our hospital were equally randomized into treatment group and control group. Results Pathogen distribution was ordered as follows： Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa, Acinetobacter baumannii, and Escherichia coli. A- mong them, Staphylococcus aureus had the biggest share and a substantial number of patients were infected by gram negative bacilli. Pan-- resistant bacteria infection and mixed in：Fection were the root causes for some hard - to - treat cases. The selection of appropriate antibiotics was particularly im- portant based on drug susceptibility test. Compared with the control group, the treatment group which received Tanreqing combined with antibiotics has better efficacy in treating HAP. Conclusions HAP mortality rate is very high among senile patients. The condition is normally very danger- ous. Tanreqing combined with antibiotics can effectively control infection and helps patients recov- er.