摘要
目的:探讨高血压患者臂踝脉搏波传导速度(BAPOWV)与血压负荷的关系。方法:入选原发性高血压患者348例,进行24 h动态血压监测和BAPWV测定,根据BAPWV的值,将其分为2组:BAPWV正常组(BAPWV<1400cm/s)121例,BAPWV升高组(BAPWV≥1400 cm/s)227例。比较2组患者年龄、性别构成比、血糖、血脂、血肌酐、血尿酸、血压及血压负荷。结果:单因素分析显示,BAPWV升高组患者的年龄、三酰甘油、胆固醇、低密度脂蛋白、血压及血压负荷均显著高于BAPWV正常组(P<0.05)。Logistic回归分析表明年龄、夜间收缩压负荷及夜间舒张压负荷是影响BAPWV的独立因素(P<0.05)。结论:高血压患者夜间收缩压负荷和舒张压负荷是影响BAPWV的独立因素。
Objective:To explore the relationship between brachial-ankle pulse wave velocity and blood pressure load in hypertensive patients. Methods:348 patients were enrolled in this study. Ambulatory blood pressure (ABP) and brachial-ankle pulse wave velocity (BAPWV) were measured. According to the value of BAPWV, all patients were divided into two groups : BAPWV normal group ( bapwv 〈 1400 cm/s, n = 121 ) and BAPWV elevated group (bapwv ≥ 1400 cm/s, n = 227). The patients' age, gender ratio, fasting blood glucose (FBG), triglyceride (TG), cholesterol (CHO), low density lipoprotein cholesterol (LDL), high density lipo- protein cholesterol (HDL), creatinine (Cr), uric acid (UA), blood pressure level and blood pressure load were measured. Results:Univariate analysies revealed that age, TG, CHO, LDL, blood pressure and blood pressure load in BAPWV elevated group were significantly higher than those in BAPWV normal group (P 〈 0.05 ). Logistic multivariate regression analysis indicated that age, nighttime systolic blood pressure load and nighttime diastolic blood pressure load were independent influencing factors of BAPWV. Conclusion:nighttime systolic blood pressure load and nighttime diastolic blood pressure load of hypertensive patients were independ- ent influencing factors of BAPWV.
出处
《心肺血管病杂志》
CAS
2012年第4期425-427,共3页
Journal of Cardiovascular and Pulmonary Diseases
关键词
肱踝脉搏波传导速度
血压负荷
高血压
Brachial-ankle pulse wave velocity
Blood pressure load
Hypertension