北京市西城区入伍体检人员甲型、戊型肝炎病毒感染状况调查分析

Infection status of hepatitis A virus and hepatitis E virus in people receiving health examination for army recruitment in Xicheng district,Beijing

目的了解北京市入伍体检人员的甲型病毒性肝炎病毒(HAV)、戊型病毒性肝炎病毒(HEV)感染状况,为肝炎病毒预防控制提供参考依据。方法采用随机抽样的方法收集北京市西城区入伍体检人员的血清,用酶联免疫吸附试验检测血清HAV-IgG、HAV-IgM、HEV-IgG及HEV-IgM指标,以速率法检测血清谷丙转氨酶水平。结果收集327例血清,男性,年龄在17～24岁之间。血清检测结果表明,HAV感染率为46.48%,HEV感染率为6.12%;HAV、HEV重叠感染的有8例,占2.45%;HAV隐性感染率为0.31%,HEV隐性感染率为2.45%。结论大部分新兵入伍体检对象是HAV和HEV的易感人群,且部分调查对象正在发生HAV、HEV隐性感染,应及时对该人群采取预防措施。

Objective To evaluate the hepatitis A virus （HAV） and hepatitis E virus （HEV） infection status in people receiving health examination for army recruitment in Beijing and provide evidence for the prevention and control of viral hepatitis. Methods The blood samples were taken form the people receiving health examination for army recruitment selected by random sampling in Xicheng district of Beijing. Enzyme linked inununosorbent assay （ELISA） was conducted to detect HAV-IgG, HAV-IgM, HEV-IgG and HEV-IgM and rate method was used to detect Alanine transaminase. Results Totally a total of 327 male subjects aged 17-24 years were enrolled in the study. The serological detection indicated that the overall HAV infection rate was 46.48%, and the overall HEV infection rate was 6. 12%. Eight （ 2.45 % ） subjects were co-infected with HAV and HEV. The subclinical infection rate of HAV was 0.31% , and the subclinical infection rate of HEV was 2.45%. Conclusion Most people who plan to join the army are susceptible for HAV and HEV infections, and subclinical infections of HAV and HEV exist in these people. It is necessary to take effective measures for the prevention of viral hepatitis in this population.