长期大量饮酒对注意网络的影响

The impact of long-term alcohol drinking heavily on the attention networks

目的探讨长期大量饮酒对注意网络的影响。方法运用注意网络测验，对长期大量饮酒者（饮酒组，33例）和无饮酒嗜好者（对照组，27例）进行注意网络功能的检查。结果长期大量饮酒组定向网络效率为（26．7±38．6）ms，显著低于对照组的（51．8±22．3）ms（t=-3．72，P〈0．01）；警觉网络、执行控制网络较对照组有改变，但差异无统计学意义（P〉0．05）。结论长期大量饮酒者存在定向网络的损害，提示过量饮酒可能会对顶叶产生毒性作用，或影响胆碱能系统导致注意功能障碍。

Objective To explore the impact of alcohol to attention networks. Methods The attention net- work test was performed in 33 alcoholics and 27 normal controls on the efficiency of three anatomically defined atten- tional networks：alerting, orienting and executive control. Results The orienting network function was significantly lower（ t = - 3.72, P 〈 0.01 ） in alcoholics （ 26.7 ± 38.6 ） ms than that in normal controls （ 51.8 ± 22.3 ） ms. The executive networks effects was higher and the alerting networks effects was lower in alcoholics than in normal controls, however without significant difference （ P 〉 0. 05 ）. Conclusion The parietal lobe and cholinergic system may be more significantly affected by the alcohol.