孕前体质量指数及孕期体质量增加与妊娠期糖尿病的相关性分析

Relationships between maternal pre-pregnancy body mass index, pregnancy weight gain and gestational diabetes

目的分析孕前体质量指数、孕期体质量增加与妊娠期糖尿病（GDM）的关系。方法对345例足月初产孕妇孕前体质量指数、孕期体质量增加值与GDM的发病情况的临床资料进行分析。结果低体质量组、理想体质量组、超体质量组的GDM发生率分别为2．78％、2．96％、16．04％，孕前超体质量组C-DM发生率明显高于理想体质量组和低体质量组（x2=4．269、17．299，均P〈0．05）；孕妇不同孕期体质量噌加（A组〈11．0kg、B组11．0～17．9kg、C组18．0～24．9kg、D组≥25．0kg）幅度，其孕妇GDM发生率分别为0、1．75％、6．60％、11．02％，孕期体质量增加A、B、C、D组GDM发生率差异有统计学意义（P〈0．05）。结论测定孕妇孕前体质量指数、孕期体质量增加值对于预测GDM的发生率具有一定临床意义。

Objective To analyze the association between pre-pregnancy body mass index,pregnancy weight gain and gestational diabetes （GDM）. Methods The pre-pregnancy body mass index, pregnancy weight gain and the incidence data of 345 gestational diabetes with full-term primiparae were analyzed. Results The GDM ratio of low- weight, ideal weight group, over-weight was 2.78% , 2.96%, 16.04% , respectively over-weight GDM pregnancy was significantly higher than the ideal weight group（ X2 =4.269 ,P 〈 0.05 ） , and GDM over-weight before pregnancy was significantly higher than the low weight group the incidence of GDM, the difference was statistically significant （ X2 = 17. 299, P 〈 0. 01 ） ; Pregnant women in different pregnancy weight gain A （ 〈 11.0kg）, B （ 11.0 - 17.9kg）, C （ 18.0 24.9kg）, D（ I〉25. Okg） range, the GDM were 0% , 1.75% ,6.60% , 11.02%, that GDM of A, B, C, D group were statistically different（ P 〈 0.05 ）. Rate of weight gain during pregnancy on pregnancy size was proportional to the im- pact of diabetes. Conclusion Pre-pregnancy body mass index, pregnancy weight gain had clinical significance in e- valuation of gestational diabetes.