摘要
目的:比较肠内及肠外营养支持治疗重症急性胰腺炎(SAP)的临床效果,探讨肠内营养(EN)的安全性、有效性及其优势。方法:将50例SAP患者随机分为两组,肠外营养(PN)组25例及肠内营养(EN)组25例,比较并分析两组主要治疗经过及临床转归、APACHEⅡ评分、CT评分、血清白蛋白和前白蛋白的变化以及免疫学指标的变化。结果:EN组较PN组能显著缩短病程,减少住院费用,降低并发症及感染率(P<0.05)。治疗后EN组APACHEⅡ及CT评分变化显著大于PN组(P<0.05),血清白蛋白、前白蛋白水平高于PN组(P<0.05),免疫学指标的改善较PN组显著(P<0.05)。结论:EN较PN更安全和有效,能显著改善SAP患者的营养状况及免疫功能、降低并发症及感染率、减少住院费用、缩短病程。
Objective：To compare enteral nutrition （EN） and parenteral nutrition （ PN ） in the treatment of severe acute pancreatitis （SAP）. Approach the safe, availability and ascendancy of enteral nutrition （EN）. Methods：Fifty patients were randomly divided into 2 groups, EN group and PN group. To compare and analyze the treatment course, clinical turnover,APACHE 11 and CT score, change of serum - albumin and prealbumin, diversity of amynology index of two sets pa- tients. Results： In EN group, hospital stay days, hospital fees, complications and infec- tion rate were significantly lower compared with PN group （ P 〈 0.05 ）. The improve- ment of APACHE II and CT score of EN group was more significant than that of PN group（P 〈 0.05 ）. Serumalbumin and prealbumin of EN group were higher than that of PN group （ P 〈 0.05 ）. The amelioration of amynology index of EN group was more significant than that of PN group （ P 〈 0.05 ）. Conclusions： It is more safe and effective than PN to give early EN support to SAP patients, which can markedly improve nutritional state and immune function, step down complications and infection rate,reduce hospital fees, shorten hospital stay days.
关键词
重症急性胰腺炎
肠内营养
肠外营养
Severe acute pancreatitis （SAP）
Enteral nutrition （ EN ）
Parenteral nutrition （PN）
