铜绿假单胞菌抗菌物质对屎肠球菌的体外抑菌作用研究

Study on in vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against Enterococcus faecium

目的:为了观察铜绿假单胞菌对屎肠球菌的体外抑菌活性。方法:用交叉条带实验方法进行铜绿假单胞菌对12株屎肠球菌的体外抑制活性的测定。结果:铜绿假单胞菌抗菌物质对屎肠球菌体外抑菌活性良好,所试10株的铜绿假单胞菌对屎肠球菌均有一定的抗菌活性,其中第1、4、5、6号株的铜绿假单胞菌对屎肠球菌抑制率达100%。结论:铜绿假单胞菌抗菌物质对12株肠球菌具有良好的抗菌活性,无疑对肠球菌的抗菌研究方面开辟了新的思路。这是首次进行铜绿假单胞菌抗菌物质对屎肠球菌的抗菌活性研究报告。

Objective：To evaluate the in vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against Enterococcus.Methods： The in vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against 12 Enterococcus faecium was performed by using the cross streak assay.Results： The in vitro inhibitory activity of antibacterial material of Pseudomonas aeruginosa against Enterococcus was good.The inhibition rates of No.1,4,5 and 6 strain of P.aeruginosas against Enterococcus faecium were all 100%.Conclusion： The antibacterial material of Pseudomonas aeruginosa against 12 Enterococcus had strong antibacterial activity,which has the potential to open a new train of thought for the antibiotics research of Enterococcus infection.This is the first report concerning antibacterial activity study for antimicrobial substances of Pseudomonas aeruginosa against Enterococcus.