摘要
To determine the diet security of brown algal polyphenols, we studied the acute toxicity and 90 day’s feed toxicity on brown algal polyphenols isolated from Sargassum kjellmanianum. The lethal dose 50 for rat is 1 230×10-6,with 95% confidence ranged from 791.4×10-6 to 1 912.4×10-6. The 90 day′s feeding experiment showed that the mouses administered brown algal polyphenols maintain regular conditions, with no difference to the control group on blood biochemical index, weight, and pathology analysis. The results indicated that brown algal polyphenols is safe as food additive.
To determine the diet security of brown algal polyphenols, we studied the acute toxicity and 90 day's feed toxicity on brown algal polyphenols isolated from Sargassum kjellmanianum. The lethal dose 50 for rat is 1 230×10-6,with 95% confidence ranged from 791.4×10-6 to 1 912.4×10-6. The 90 day′s feeding experiment showed that the mouses administered brown algal polyphenols maintain regular conditions, with no difference to the control group on blood biochemical index, weight, and pathology analysis. The results indicated that brown algal polyphenols is safe as food additive.
出处
《海洋科学》
CAS
CSCD
北大核心
2000年第9期53-55,共3页
Marine Sciences
基金
国家九五攻关项目!966 916 04 01号
中国科学院海洋研究所调查研究报告第3834号
关键词
褐藻多酚
食用安全性
毒理
Brown algal polyphenol, Diet security, Toxicology
