8860份住院病历中的药物过敏史调查与分析

Investigation and Analysis of Allergic History to Medications in 8860 Hospital Records

目的为进一步防止药物过敏反应,保证患者用药安全。方法回顾性调查8860份住院病历中药物过敏史情况,探讨头孢菌素类进行皮肤敏感性试验的必要性。结果与结论在药物过敏史中,青霉素类过敏反应率最高(37.8%),精制破伤风抗毒素、磺胺类、头孢菌素类的过敏反应率分别是15.8%,11.5%,11.3%。开展头孢菌素皮肤敏感性试验是非常必要的。

Objective To retrospective investigate the allergic history to medications in 8860 hospital records.Methods 8860 hospital records were investigated in our hospital to discuss the necessity of skin test of cephalosporin.Results and Condusion Among the allergic history,the proportion of penicillins was the highest（37.8%）,that of TAT,sulfanilamide,cephalosporins was 15.8%,11.5%,11.3%.Skin test should be done before administration of cephalosporins so as to prevent drug allergy and ensure the safety of drug use.