经口内镜下肌切除术治疗贲门失弛缓症的临床疗效观察

The clinic effect of peroral endoscopic myotomy for achalasia

目的观察经口内镜下肌切除术（POEM）治疗贲门失弛缓症的临床疗效和安全性。方法对2010年11月至2011年11月7例确诊为贲门失弛缓症的患者行POEM手术。记录术前吞咽困难评分、术后并发症及近期远期疗效。结果7例患者POEM手术均成功。手术时间46～113min，平均（73±ao）min。术后除2例出现皮下气肿、纵隔气肿，经内科治疗后痊愈，余均未出现相关并发症。术后随访1—12个月，7例患者吞咽困难均得到明显改善。结论POEM手术可以迅速解除贲门失弛缓症患者吞咽困难，且具有一定的安全性。

Objective To evaluate the effects and the safety of peroral endoscopic myotomy （POEM） for aehalasia （AC）. Methods POEM was performed on 7 AC patients from November 2010 to November 2011. Preoperative dysphagia grade, postoperative complications and short-term and long-term efficacy were recorded. Results POEM was performed successfully on all the 7 patients. The operation time were ranging from 46 to 113 minutes ,mean 73±20 minutes. Subcutaneous emphysema and mediastinal em- physema occurred in 2 patients, but cured after treatment. The 1-12 month follow-up showed dysphagia of all the patients was obviously improved. Conclusion POEM is efficient and safe to relieve dysphagia of AC patients.