摘要
该文针对中药制剂的研究现状,以"整体观念"和"辨证论治"为指导,依据中药多组分、多靶点、多效应的特点,提出"基于物质基础组分的中药多元释药系统"研究思路,建立"以物质基础组分为前提,以提高生物利用度为目的,构建中药多元释药系统"的中药制剂研究新模式,并以通脉微丸多元释药系统为例进行阐述,为中药现代给药系统的深入发展提供新的策略和方法。
To aim directly at the research status of Chinese drugs pharmaceutics, this study provides a new research idea ＂traditional Chinese medicine multiple drug delivery system based on material basis component＂. This thought according to whole concept, syndrome, and Chinese medicine characteristics of multi-component, multi-target, muhi-effect. The premise of designing traditional Chinese medicine multiple drug delivery system is material basis component, and the purpose is to improve bioavailability. The example of multi-drug delivery system of tongmai micro-pellets is expounded for application. This new research model of Chinese drugs pharmaceutics provides new strategies and methods for the development of modern Chinese drug delivery systems.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第14期2181-2185,共5页
China Journal of Chinese Materia Medica
基金
江苏省中医药领军人才项目(2006)
中药制药过程新技术国家重点实验室开放基金项目(SKL2010Z0303)
江苏省中医药科技项目(LZ09061,LZ09067)
关键词
中药多元释药系统
物质基础组分
生物利用度
通脉微丸
traditional Chinese medicine muhiple drug delivery system
material basis component
bioavailability
Tongmai micro-pellets
