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大黄素脂质纳米微泡的制备及性能研究 被引量:1

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摘要 目的:制备大黄素脂质纳米微泡,并对其理化性能进行初步研究。方法:以卵磷脂和PVP为载体材料,采用静电纺丝技术制备纳米纤维膜,填充全氟丙烷,通过自组装技术形成脂质纳米微泡,并对其粒径、分布、形态、表面电位等性能进行研究。结果:所制备的脂质纳米微泡为圆形,粒度分布均匀,平均粒径235.9 nm,电位-31.6mV,多分散指数PDI=0.331。结论:整合运用高压静电纺丝技术和自组装技术制备大黄素脂质纳米微泡是可行的,该方法简单可靠,有开发的前景。
出处 《中药材》 CAS CSCD 北大核心 2012年第5期813-815,共3页 Journal of Chinese Medicinal Materials
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