淮南市2004～2011年麻疹病例IgM抗体检测结果分析

Analysis of the results of IgM antibody detecting in suspected measles cases in Huainan city from 2004 to 2011

目的分析淮南市2004-2011年麻疹实验室检测结果,为控制和消除麻疹提供实验室诊断依据。方法对淮南市2004-2011年麻疹监测系统发现的疑似麻疹病例,进行实验室血清学检测结果与流行病学分析。结果淮南市2004-2011年共检测麻疹疑似病例标本851份,其中麻疹IgM抗体阳性标本457份,阳性率53.7%,各县、区均有麻疹IgM抗体阳性病例,发病高峰在每年的3-5月份,近3年麻疹发病人群向<8月龄儿童和≥15岁人群移动。结论通过检测麻疹IgM抗体,对麻疹疑似病例进行早期血清学诊断,对麻疹疫情的确认和及时采取预防措施提供了依据。

Objective To analyze the laboratory test results for measles in huainan from 2004 to 2011,and provide a diagnostic evidence for measles control and elimination.Methods Serological test and descriptive epidemiology method were used in suspected measles cases from measles surveillance system.Results A total of 851 serum samples of suspected measles cases were detected from 2004 to 2011,with 457（53.7%） were measles IgM-positive cases.Suspected measles cases with positive IgM results covered all the counties.The peak incidence was found during the period of March to May.Most cases aged below 8 months and above 15 years.Conclusion Early serological diagnosis of suspected measles by detection of IgM antibodies could provide basis for determination of measles epidemic and taking measures timely.