摘要
目的:观察呋塞米联合甘露醇治疗高血压脑病的疗效及安全性。方法:对42例高血压脑病患者从入院时即予呋塞米20 mg静脉注射,20%甘露醇250 mL静滴联合治疗,动态评估患者血压变化和临床症状改善情况,并观察其不良反应。结果:42例高血压脑病患者在用药(25±5)min后开始自觉症状改善;舒张压和平均压缓慢下降,30 min后出现明显下降;60 min时所有患者均达到目标血压;未发现明显不良反应。结论:呋塞米联合甘露醇在降低颅内压的同时,能平稳降低血压,简单、便捷、安全,可应用于无合并严重肾衰、心衰的高血压脑病患者。
Objective： To evaluate the efficacy and safety of furosemide and mannitol in the treatment of hypertensive eneephalopathy. Methods： 42 patients with hypertensive encephalopathy received furosemide 20 mg intravenously while using 20% mannitol 250 mL infusion,and then observed the dynamic change of BP,clinical symptoms and bad reaction. Results.： The subjective symptoms of patients improved markedly after （25±5）min of the treatment. DBP and MAP decreased slowly and obviously decreased after treatment 30 minutes. All cases obtained the target of BP at 60 min and no obvious side effects. Conclusion： The results suggest that the combination of intravenous furosemide and mannitol is a simple safe and efficient method in treatment of hypertensive encephalopathy.
出处
《岭南急诊医学杂志》
2012年第1期24-25,共2页
Lingnan Journal of Emergency Medicine
关键词
呋塞米
甘露醇
联合治疗
高血压脑病
疗效
furosemide
mannitol
combined therapy
hypertensive encephalopathy
efficacy
