张堰镇企业从业人员代谢综合征与脂肪肝的相关性研究

Association between Metabolic Syndrome and Fatty Liver among Employees in Zhangyan Town

目的了解上海市金山区张堰镇企业从业人员代谢综合征(MS)和脂肪肝在不同性别、年龄等的患病率,以及探讨代谢综合征与脂肪肝的相关性。方法通过分析10 437例从业人员体检数据,用χ2检验比较MS与脂肪肝患病率的差异。采用多因素逐步logistic回归分析对脂肪肝的危险因素进行分析,比较脂肪肝组和非脂肪肝组不同指标患病率的优势比(Odds ratio,OR)。结果代谢综合征与脂肪肝的患病率随年龄增加而增加,男性代谢综合征和脂肪肝的患病率高于女性(P<0.001);除血脂紊乱外,其他各项的患病率在>20年工龄组中高于≤10年组和11～20年组。结论从上海市金山区张堰镇企业从业人员的体检数据可以看出,MS与脂肪肝的患病率较高,MS与脂肪肝有密切的关系。脂肪肝可作为MS的组分进行观察,进行早期的脂肪肝筛检,有助于提早发现MS。本研究为脂肪肝与MS的相关性研究提供理论依据。

Objective To understand the prevalence of metabolic syndrome（MS） and fatty liver in different gender and age employees from the firms in Zhangyan Town Jinshan District of Shanghai and investigate the association between the metabolic syndrome and the fatty liver. Methods The medical data of 10,437 employees were collected. The chi-square test was used to com- pare the differences in prevalence between MS and fatty liver. The muhivariable stepwise logistic regression analysis was used to analyze the risk factors of fatty liver, and compare the different indicators of prevalence odds ratio（ Odds ratio, OR） in fat liver group and the non-fatty liver group. Results The prevalence of metabolic syndrome and fatty liver increased with the age, and the incidence of MS and fatty liver in male were higher than those in female （P 〈 0.001 ） ;In addition to dyslipidemia, the incidences of other diseases in the group with service period over 20 years were higher than those in the group with the service period less than 10 years and between 11 and 20 years. Conclusion The prevalence of MS and fatty liver is high;MS and fatty liver are closely related. Fatty liver can be observed as the components of MS, and the early screening of the fatty liver can contribute to detecting the MS. This study can also provide a theoretical basis to the correlation of the fatty liver and the MS.