大叶冬青三萜糖甙结构的研究

STUDY ON THREE NEW TRITERPENES BY NMR TECHNIQUES

利用二维核磁技术 ,特别是反转模式的HMQC和HMBC ,对从大叶冬青植物分离得到的三个五环三萜大叶冬青甙Ⅰ、Ⅱ和Ⅲ新化合物的结构进行确定 .含糖较多的糖结构的确定包括1 3CNMR谱的归属 ,糖基的类型、糖 1位的构型、糖与糖、糖与甙元之间的接点和连接顺序等问题作了深入的研究 .

The concerted application of a variety of one and two dimensional NMR techniques to the structural elucidation of the three natural products:latifoliasida Ⅰ,Ⅱ,Ⅲ isolatated from Ilex Latifolia, in C\-5D\-5N solution are reported. Especially the techniques of 2D NMR(TOCSY,HMQC, and HMBC), let us solve the problem such as the anomeric configuration, linkages between sugar and sugar, between the aglycone and sugar. These spectra provide valuable information for assigning the \{\}\+\{13\}C NMR resonance of this class of compounds. \;