摘要
目的:优选川乌高温烘制工艺。方法:HPLC和滴定法测定炮制品中6种生物碱和总生物碱的含量,并以此为指标,选取烘制时间、烘制温度及软化方式等为考察因素,采用正交试验法综合评价其高温烘制工艺。结果:川乌高温烘制的最佳工艺为A5B3C1,即川乌经润透法处理,110℃烘制8 h。结论:该优选工艺简单可行且易于控制,可替代川乌传统炮制工艺。
Objective： To optimize high temperature baking process of Aconitum carmichaeli.Method： With the content of six kinds of alkaloid and total alkaloids in processed products were determined by HPLC and titration method,and with them as indexes,taking baking time,baking temperature and softening method as factors,orthogonal test was used to comprehensive evaluate high temperature baking technology of A.carmichaeli.Result： Optimum high temperature baking technology of A.carmichaeli was A5B3C1,as that of A.carmichaeli was treatmented by moistening method,baked 8 h at 110 ℃.Conclusion： This optimized technology was simple,practical and easy to control,it could be instead of traditional processing technology of A.carmichaeli as a new method.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第15期51-54,共4页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
川乌
双酯型生物碱
单酯型生物碱
总生物碱
高温烘制
正交设计
Aconitum carmichaeli
diesterifiable alkaloids
monoester alkaloids
total alkaloids
high temperature baking
orthogonal design
