通痹汤治疗强直性脊柱炎的临床疗效分析

Clinical Curative Effect Analysis on Combine Tongbi Decoction and Western Medicine Treatment for Ankylosing Spondylitis

目的:观察中西医结合治疗强直性脊柱炎的临床效果。方法:选取80例发病时间在3个月以内的强直性脊柱炎患者,并随机分为两组,40例患者口服吲哚美辛肠溶片和布洛芬治疗作为对照组,40例患者在对照组基础上加服自拟通痹汤,两组患者均治疗3个月,观察比较两组患者治疗效果。结果:观察组患者治疗总有效率为92.50%,对照组患者治疗总有效率为77.50%,两组患者治疗效果有显著差异(P<0.05)。两组患者治疗前血沉(ESR),慢反应物质(CRP)及免疫球蛋白A(IgA)无显著差异,治疗后观察组ESR,CRP及IgA分别为(8.05±3.02)mm·h-1,(7.25±3.52)mg·L-1,(1.58±0.87)mg·L-1,对照组ESR,CRP及IgA分别为(14.56±6.12)mm·h-1,(12.32±6.27)mg·L-1,(3.02±0.89)mg·L-1,两组差异显著(P<0.05)。结论:中西医结合治疗强直性脊柱炎可达到更理想的治疗效果。

Objective： To observe clinical effect of the combine Tongbi decoetion and western medicine treatment for ankylosing spondylitis.Method： Eighty cases of ankylosing spondylitis appeared within three months were randomly divided into two groups： 40 patients were treated by oral indomethacin enteric-coated metformin hydrochloride and ibuprofen as control group,the other 40 patients were treated by Tongbi decoction combine the above metioneal western medicine.Two groups of patients were treated for 3 months,and the therapeutic effect was evaluated.Result： In the observation group the total effective rate was 92.50%,and in the control group the total effective rate was 77.50%,with significant difference（P0.05）.Before treatment two groups showed no differences in erythrocyte sedimentation rate（ESR）,creaction protein（CRP） and Immunog otulin A（IgA） after treatment,in the observation group ESR,CRP and IgA were（8.05±3.02） mm·h-1,（7.25±3.52）mg·L-1 and（1.58±0.87）mg·L-1,in control group ESR,CRP and IgA were（14.56±6.12） mm·h-1,（12.32±6.27）mg·L-1 and（3.02±0.89） mg·L-1,with significant difference（P0.05）.Conclusion： Combine Tongbi decoction and western medicine treatment of ankylosing spondylitis could achieve benefical effect,and the approach is promising.