岭南地区冠心病心绞痛患者中医体质分布规律

The Constitution Distribution of Angina Pectoris Patients in Lingnan Area

目的探讨岭南地区冠心病心绞痛患者中医体质类型分布情况并探讨其与超敏C反应蛋白(hs-CRP)、血脂水平之间的相关性。方法收集岭南地区冠心病心绞痛患者89例,进行中医体质证型判定,测定其血清hs-CRP、血脂水平并与健康志愿者10例(对照组)进行对照。结果冠心病心绞痛患者以血瘀质(34.83%)、痰湿质(22.47%)、湿热质(20.23%)为主,各类型体质冠心病心绞痛患者hs-CRP、血脂水平与对照组比较差异均有统计学意义(P<0.01)。湿热质、痰湿质、血瘀质患者hs-CRP、血脂水平较其他类型体质患者有明显升高,差异具有统计学意义(P<0.05)。结论岭南地区痰湿质、湿热质及血瘀质的人更容易患冠心病心绞痛,hs-CRP、血脂水平升高与痰湿质、湿热质及血瘀质冠心病心绞痛患者之间密切相关。

Objective To research the constitution distribution of patients with angina pectoris and its correlation with high- sensitivity C-reactive protein （hs-CRP）, low-density lipoprotein cholesterol （LDL-C） and total cholesterol （TC）. Methods Eighty nine angina peetoris patients and 10 healthy volunteers lived in Lingnan area Guangdong Province were observed based on their constitution in Chinese medicine. The levels of hs-CRP, LDL-C and TC were detected and contrasted. Results The most common constitution types of angina pectoris patients are constitution of blood stasis （34.83%）, phlegm-damp （22. 47%） and damp-heat （20.23%）. Comparing the control group, there were significant differences between patients and healthy volun- teers with different constitution in hs-CRP level, LDL-C and TC （P〈0.01）. The levels of hs-CRP, LDL-C and TC were sig- nificantly increased in the patients with constitution of damp-heat, phlegm-damp and blood stasis （P〈0.05）. Conclusion People with constitution of damp-heat, phlegm-damp and blood stasis in Lingnan area are more likely to suffer from angina pec- toris. The elevation of hs-CRP, LDL-C and TC is closely related to angina pectoris patients with constitution of damp-heat, phlegm-damp and blood stasis.