利用超临界萃取装置精馏回收聚乙二醇400工艺

Using Supercritical Fluid Extraction Device to Recycle PEG-400 as Solvent for Preparation of Conjugated Linoleic Acid

利用超临界流体萃取装置精馏回收碱异构化制取共轭亚油酸的溶剂聚乙二醇400,研究精馏条件对反应体系中的溶剂聚乙二醇400分离效果的影响。通过单因素试验确定最佳分离条件为精馏压力10MPa、四级精馏温度25-35-45-55℃、精馏时间3h,此时聚乙二醇400回收率70.06%,纯度97%。通过单因素方差分析可知,精馏压力、精馏温度、精馏时间均对聚乙二醇400的回收率具有显著影响。

A supercritical fluid extraction device was used to recycle the solvent polyethylene glycol （PEG） 400 left over after the preparation of conjugated linoleic acid （CLA） by alkali isomerization in this study. The effects of various extraction conditions on the separation of PEG-400 were investigated. The optimal extraction conditions were determined as extraction pressure of 10 MPa, four-step extraction temperatures of 25-35-45-55 ~C and extraction time of 3 h. Under these conditions, the recycling rate of PEG-400 was up to 70.06%, and the purity of PEG-400 was 97%. The results of one-way ANOVA showed that extraction pressure, temperature and extraction time had a marked effect on the recycling of PEG 400.