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姜黄素联合吉西他滨对人胰腺癌Panc-1细胞增殖的影响 被引量:6

Effects of curcumin combined with gemcitabine on the proliferation of human pancreatic cancer Panc-1 cells
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摘要 目的探讨姜黄素联合吉西他滨对人胰腺癌Panc-1细胞增殖的影响。方法培养人胰腺癌Panc-1细胞,分别与姜黄素(60μmol/L)、吉西他滨(20μmol/L)、两药联合(姜黄素+吉西他滨)培养24,48和72 h,采用CCK-8(Cell Counting Kit-8)法检测各组Panc-1细胞的存活率。结果姜黄素和吉西他滨单独作用以及姜黄素联合吉西他滨组均能明显抑制Panc-1细胞增殖,呈时间依赖性;姜黄素联合吉西他滨组抑制Panc-1细胞增殖作用明显强于任一单独用药组,且呈时间依赖性。结论姜黄素联合吉西他滨对人胰腺癌Panc-1细胞增殖具有明显的抑制作用。
出处 《中国生化药物杂志》 CAS CSCD 北大核心 2012年第4期449-451,共3页 Chinese Journal of Biochemical Pharmaceutics
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