2009-2010年我院急诊ICU感染致病菌分布及抗菌药物应用分析

Distribution of Infection Pathogenic Bacteria in EICU and Analysis of the Use of Antibacterial Drugs in Our Hospital from 2009 to 2010

目的:了解我院急诊重症监护病房(ICU)感染致病菌的分布特点及耐药情况,为临床合理选择抗菌药物提供依据。方法:回顾性调取2009-2010年我院急诊ICU检出感染致病菌的相关数据,并结合同期急诊ICU抗菌药物的应用情况进行分析。结果:2年间急诊ICU共检出感染致病菌781株,其中革兰阴性菌639株,占总菌数的81.82%;革兰阴性菌以铜绿假单胞菌、鲍曼不动杆菌、大肠埃希菌、肺炎克雷伯菌为主,革兰阳性菌以金黄色葡萄球菌和表皮葡萄球菌为主。结论:明确急诊ICU的菌株变迁和细菌耐药率,有利于合理选择敏感抗菌药物。

OBJECTIVE：To investigate the distribution of the infection pathogenic bacteria and drug resistance in EICU department of our hospital,and to provide clinical reference for rational use of antibacterial drugs.METHODS：The data of infection pathogenic bacteria were collected from EICU of our hospital during 2009-2010 retrospectively.The application of antibacterial drugs in EICU was analyzed at the same period.RESULTS：781 strains of infection pathogenic bacteria were detected in EICU department from 2009 to 2010,the number of Gram-negative bacillus was 639,accounting for 81.82%.Among Gram-negative bacteria,Pseudomonas aeruginosa,Acinetobacter baumannii,Escherichia coli,Klebsiella pneumoniae were the major ones.Among gram-positive bacteria,Staphylococcus aureus and Staphylococcus epidermidis were the most prominent.CONCLUSION：Understanding the change of bacteria and the increase of drug resistance rate contribute to rational selection of antibacterial drugs.